IA1-8H2

IA1-8H2

• CAS Number: 2755685-19-7
• UNSPSC Description: IA1-8H2 is a non-covalent, non-competitive inhibitor of PHPT1 (IC50: 3.4 μM). IA1-8H2 can be used for research of lung cancer, hepatocarcinoma, and renal cancer[1].
• Target Antigen: Phosphatase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ia1-8h2.html
• Solubility: 10 mM in DMSO
• Smiles: OC(CC1=C2C3=C(CCC3)C(O)=C1C=O)OC2=O
• Molecular Weight: 248.23
• References & Citations: [1]Wang H, et al. Derivatives of the Fungal Natural Product Illudalic Acid Inhibit the Activity of Protein Histidine Phosphatase PHPT1. ChemMedChem. 2023 Aug 1;18(15):e202300187.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported