SARS-CoV-2-IN-58

SARS-CoV-2-IN-58

• UNSPSC Description: SARS-CoV-2-IN-58 (Compound 21H) is an antiviral agent against SARS-CoV-2 (EC50: 18 μM). SARS-CoV-2-IN-58 inhibits SARS-CoV-2 Mpro with an IC50 of 0.35 μM[1].
• Target Antigen: SARS-CoV; Virus Protease
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-in-58.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC2=C(N1CC(C)C)C=CC(Cl)=C2)NCCCNC(N3C=C(F)C(NC3=O)=O)=O
• Molecular Weight: 463.89
• References & Citations: [1]Kang KM, et al. Discovery of antiviral SARS-CoV-2 main protease inhibitors by structure-guided hit-to-lead optimization of carmofur. Eur J Med Chem. 2023 Nov 15;260:115720.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported