SARS-CoV-2 3CLpro-IN-16

SARS-CoV-2 3CLpro-IN-16

• CAS Number: 352659-40-6
• UNSPSC Description: SARS-CoV-2 3CLpro-IN-16 (Compound 3a) is a covalent SARS-CoV-2 3CLpro inhibitor (IC50s: 2.124 μM). SARS-CoV-2 3CLpro-IN-16 binds to the active site and forms a covalent bond with Cys145 of 3CLpro[1].
• Target Antigen: SARS-CoV
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-anti-virus
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/sars-cov-2-3clpro-in-16.html
• Solubility: 10 mM in DMSO
• Smiles: N#CSCC(N1C2=C(CCC3=C1C=CC=C3)C=CC=C2)=O
• Molecular Weight: 294.37
• References & Citations: [1]Ren P, et al. Discovery and Mechanism Study of SARS-CoV-2 3C-like Protease Inhibitors with a New Reactive Group. J Med Chem. 2023 Aug 18.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported