CDK2-IN-19

CAT: 0804-HY-155966Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-155966Size:1 Each
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Description
CDK2-IN-19 (Compound 32) is a selective and orally active CDK2 inhibitor (Ki: 0.18 nM) . CDK2-IN-19 shows anticancer activity in mice bearing OVCAR3 tumors[1].
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk2-in-19.html
Solubility
10 mM in DMSO
Smiles
FC(C=C(S(=O)(NC)=O)C=C1)=C1NC2=NC=C3C(N=C(C(N4C[C@@H](OC)[C@@H]4C)=O)C=C3)=N2.FC(C=C(S(=O)(NC)=O)C=C5)=C5NC6=NC=C7C(N=C(C(N8C[C@H](OC)[C@H]8C)=O)C=C7)=N6
Molecular Formula
C20H21FN6O4S
Molecular Weight
460.48
References & Citations
[1]Mingshuo Zeng, et al. Discovery of Selective Tertiary Amide Inhibitors of Cyclin-Dependent Kinase 2 (CDK2) . ACS Med. Chem. Lett. 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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