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Syk-IN-8

CAT: 0804-HY-155513Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155513Size:1 Each
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Description
Syk-IN-8 (compound 19q) is a Syk inhibitor, with antiproliferative activity against multiple hematological tumour cells. Syk-IN-8 inhibits PLCγ2 phosphorylation, can be used for research in blood cancers[1].
CAS Number
2568963-01-7
UNSPSC
12352005
Target
Syk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/syk-in-8.html
Solubility
10 mM in DMSO
Smiles
CC(C)N1CCN(CC1)C2=CC=C3N=C(NC3=C2)C4=NNC=C4NC5=C6C(NC=C6)=NC=N5
Molecular Formula
C23H26N10
Molecular Weight
442.52
References & Citations
[1]Bingbing Cui, et al. Discovery of 3- (1H-benzo[d]imidazole-2-yl) -1H-pyrazol-4 -amine derivatives as novel and potent syk inhibitors for the treatment of hematological malignancies. European Journal of Medicinal Chemistry. Volume 258, 5 October 2023, 115597.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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