Syk-IN-8

Syk-IN-8

• CAS Number: 2568963-01-7
• UNSPSC Description: Syk-IN-8 (compound 19q) is a Syk inhibitor, with antiproliferative activity against multiple hematological tumour cells. Syk-IN-8 inhibits PLCγ2 phosphorylation, can be used for research in blood cancers[1].
• Target Antigen: Syk
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/syk-in-8.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C)N1CCN(CC1)C2=CC=C3N=C(NC3=C2)C4=NNC=C4NC5=C6C(NC=C6)=NC=N5
• Molecular Weight: 442.52
• References & Citations: [1]Bingbing Cui, et al. Discovery of 3-(1H-benzo[d]imidazole-2-yl)-1H-pyrazol-4 -amine derivatives as novel and potent syk inhibitors for the treatment of hematological malignancies. European Journal of Medicinal Chemistry. Volume 258, 5 October 2023, 115597.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported