Syk-IN-6
CAT:
804-HY-151634
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Syk-IN-6
- CAS Number: 3018859-95-2
- UNSPSC Description: Syk-IN-6 is an inhibitor of the lipid-SH2 domain interaction, control the cellular activity of kinases containing SH2 domain. Syk-IN-6 blocks Syk kinase activity, which associated hematopoietic malignancies, including acute myeloid leukemia (AML)[1].
- Target Antigen: ERK; STAT; Syk
- Type: Reference compound
- Related Pathways: JAK/STAT Signaling;MAPK/ERK Pathway;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
- Applications: Cancer-Kinase/protease
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/syk-in-6.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C(C(NC1=NC=CC=N1)C2=CNC3=C2C=CC=C3)=[N+]=[N-])OC4CCCCC4
- Molecular Weight: 390.44
- References & Citations: [1]Singaram I, et al. Targeting lipid-protein interaction to treat Syk-mediated acute myeloid leukemia. Nat Chem Biol. 2022 Oct 13.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported