Syk-IN-3

Syk-IN-3

• CAS Number: 1312534-69-2
• UNSPSC Description: Syk-IN-3, a potent spleen tyrosine kinase (Syk) inhibitor, extracted from patent WO2011075515A1, compound example 152, has an IC50 of 1 nM[1].
• Target Antigen: Syk
• Type: Reference compound
• Related Pathways: Protein Tyrosine Kinase/RTK
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/syk-in-3.html
• Solubility: 10 mM in DMSO
• Smiles: O=C([C@@H]1C(C)(C)C[C@](C2=NC=C(C3=CC(NC4=NC=CC(C)=N4)=CC(C)=C3)S2)(O)CC1)O
• Molecular Weight: 452.57
• References & Citations: [1]Muller S, et al. Donated chemical probes for open science.CITE THIS ARTICLEAS: eLife 2018;7:e34311.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported