Syk-IN-3

CAT: 0804-HY-130680Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-130680Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1312534-69-2

UNSPSC Description

Syk-IN-3, a potent spleen tyrosine kinase (Syk) inhibitor, extracted from patent WO2011075515A1, compound example 152, has an IC50 of 1 nM[1].

Target Antigen

Syk

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/syk-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C([C@@H]1C(C)(C)C[C@](C2=NC=C(C3=CC(NC4=NC=CC(C)=N4)=CC(C)=C3)S2)(O)CC1)O

Molecular Weight

452.57

References & Citations

[1]Muller S, et al. Donated chemical probes for open science.CITE THIS ARTICLEAS: eLife 2018;7:e34311.

Shipping Conditions

Room temperature

Clinical Information

No Development Reported

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