Caspase-3-IN-1

Caspase-3-IN-1

• CAS Number: 872254-32-5
• UNSPSC Description: Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM[1].
• Target Antigen: Caspase
• Type: Reference compound
• Related Pathways: Apoptosis
• Field of Research: Metabolic Disease; Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/caspase-3-in-1.html
• Smiles: O=S(C1=CC=C(C(C(C2=O)=O)=C1)N2CC3=CC=C(C=C3)OC)(N4[C@@H](CCC4)COC5=CN=CC=C5)=O
• Molecular Weight: 507.56
• References & Citations: [1]Chu W, et al. N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies. J Med Chem. 2005 Dec 1;48(24):7637-47.
• Shipping Conditions: Room Temperature