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Caspase-3 activator 2

CAT: 0804-HY-155389Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155389Size:1 Each
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Description
Caspase-3 activator 2 (Compound 2f) is a caspase 3 activator that induces apoptosis and can be used in cancer research. Caspase-3 activator 2 is cytotoxic to HL-60 cells and K562 cells, with IC50 values of 33.52 μM and 76.90 μM respectively[1].
CAS Number
2999724-52-4
UNSPSC
12352005
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/caspase-3-activator-2.html
Solubility
10 mM in DMSO
Smiles
CN(CC1)CCN1C(C=C2)=CC=C2C(CC(C3=CSC=C3)=N4)N4C5=CC=C(F)C=C5
Molecular Formula
C24H25FN4S
Molecular Weight
420.55
References & Citations
[1]Altıntop M D, et al. Design, Synthesis, and Evaluation of a New Series of 2-Pyrazolines as Potential Antileukemic Agents[J]. ACS Omega, 2023.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported