GLS1 Inhibitor-7

• UNSPSC Description:

  GLS1 Inhibitor-7 (compound 4d) is a GLS1 inhibitor (IC50=46.7 μM), with potential anti-cancer, anti-aging and anti-obesity properties[1].

• Target Antigen:

  Glutaminase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Cancer; Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/gls1-inhibitor-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC=C(CNC(CSC2=NN=C(NC(C3=CC=C(C(F)(F)F)C=C3)=O)S2)=O)C=C1

• Molecular Weight:

  482.50

• References & Citations:

  [1]Okada T, et al. Design and structural optimization of thiadiazole derivatives with potent GLS1 inhibitory activity. Bioorg Med Chem Lett. 2023 Sep 1;93:129438.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported