α-Glucosidase-IN-30

α-Glucosidase-IN-30

• CAS Number: 2966859-35-6
• UNSPSC Description: α-Glucosidase-IN-30 (compound 8c) is a potent, orally active, competitive inhibitor against α-glucosidase, with Ki  of 40.0 µM and IC50 value of 49.0 µM. α-Glucosidase-IN-30 is non-cytotoxic against the cancer and normal cell lines MCF-7 and HDF, and can be used for Type 2 diabetes study[1].
• Target Antigen: Glycosidase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/α-glucosidase-in-30.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NCC1=CN(CC(NC2=CC(C)=CC=C2)=O)N=N1)C3=NC4=CC=CC=C4N3
• Molecular Weight: 389.41
• References & Citations: [1]Yousefnejad F, et al. Design, synthesis, in vitro, and in silico evaluations of benzo[d]imidazole-amide-1,2,3-triazole-N-arylacetamide hybrids as new antidiabetic agents targeting α-glucosidase. Sci Rep. 2023;13(1):12397.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported