α-Glucosidase-IN-44

• UNSPSC Description:

  α-Glucosidase-IN-44 (compound IT4) is an inhibitor of α-glucosidase with IC50 value of 2.35 μM. α-Glucosidase-IN-44 has an oral activity. α-Glucosidase-IN-44 suppresses fasting blood glucose levels in diabetic mice[1].

• Target Antigen:

  Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/α-glucosidase-in-44.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NCCC1=CNC2=C1C=CC=C2)CN3C(S/C(C3=O)=C\C4=CC=C(C)C=C4)=O

• Molecular Weight:

  419.50

• References & Citations:

  [1]Chunmei Hu, et al. Synthesis and biological evaluation of indole derivatives containing thiazolidine-2,4-dione as α-glucosidase inhibitors with antidiabetic activity. Eur J Med Chem. 2023.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported