α-Glucosidase-IN-25

• UNSPSC Description:

  α-Glucosidase-IN-25 (Compound (R)-8k) is a competitive inhibitor of α-glucosidase, with an IC50 of 1.19μM and can be used for anti-diabetic research[1].

• Target Antigen:

  Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/α-glucosidase-in-25.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC([C@H]1C2=CC=CC(OCC3=CN(CC4=CC=CC=C4)N=N3)=C2)=C(N)OC5=C1C(NC6=C5C=CC=C6)=O

• Molecular Weight:

  502.52

• References & Citations:

  [1]Esmaili S, et.al. Novel Pyrano[3,2-c]quinoline-1,2,3-triazole Hybrids as Potential Anti-Diabetic Agents: In Vitro α-Glucosidase Inhibition, Kinetic, and Molecular Dynamics Simulation. ACS Omega. 2023 Jun 20;8(26):23412-23424.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2941473-92-1