α-Glucosidase-IN-9

• UNSPSC Description:

  α-Glucosidase-IN-9 (compound 7) is a potent α-glucosidase inhibitor, with an IC50 of 55.6 μM. α-Glucosidase-IN-9 can be used for type II diabetes research[1].

• Target Antigen:

  Glycosidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/α-glucosidase-in-9.html

• Solubility:

  10 mM in DMSO

• Smiles:

  N#CC1=C(C2=CC=C(O)C=C2)C(C#N)=C(SC3=CC=CC=C3)N=C1N

• Molecular Weight:

  344.39

• References & Citations:

  [1]Ali M, et al. Synthesis, in vitro and in silico screening of 2-amino-4-aryl-6-(phenylthio) pyridine-3,5-dicarbonitriles as novel α-glucosidase inhibitors. Bioorg Chem. 2020 Jul;100:103879.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  735273-33-3