Gamma-Glutamyl Transferase-IN-2

• UNSPSC Description:

  Gamma-Glutamyl Transferase-IN-2 (compound 4dq) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to glutamyltransferase. Gamma-Glutamyl Transferase-IN-2 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation[1].

• Target Antigen:

  Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/gamma-glutamyl-transferase-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=NC(C(N)=O)=CC2=C1NC3=CC=CC=C32)NNC4=C(C=C(C=C4)F)F

• Molecular Weight:

  381.34

• References & Citations:

  [1]Sheng T, et al. Chromatography-Free Synthesis of β-Carboline 1-Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of 尾-Carbolines as Promising Antifungal and Antibacterial Candidates. J Med Chem. 2023 Jul 13;66(13):9040-9056.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2956809-82-6