Gamma-Glutamyl Transferase-IN-2

Gamma-Glutamyl Transferase-IN-2

• CAS Number: 2956809-82-6
• UNSPSC Description: Gamma-Glutamyl Transferase-IN-2 (compound 4dq) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to glutamyltransferase. Gamma-Glutamyl Transferase-IN-2 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation[1].
• Target Antigen: Fungal
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/gamma-glutamyl-transferase-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=NC(C(N)=O)=CC2=C1NC3=CC=CC=C32)NNC4=C(C=C(C=C4)F)F
• Molecular Weight: 381.34
• References & Citations: [1]Sheng T, et al. Chromatography-Free Synthesis of β-Carboline 1-Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of 尾-Carbolines as Promising Antifungal and Antibacterial Candidates. J Med Chem. 2023 Jul 13;66(13):9040-9056.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported