Gamma-Glutamyl Transferase-IN-1

• UNSPSC Description:

  Gamma-Glutamyl Transferase-IN-1 (compound 4de) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to glutamyltransferase. Gamma-Glutamyl Transferase-IN-1 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation[1].

• Target Antigen:

  Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/gamma-glutamyl-transferase-in-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NNC1=CC=C(F)C=C1)C2=NC(C(N)=O)=CC3=C2NC4=CC=CC=C43

• Molecular Weight:

  363.35

• References & Citations:

  [1]Sheng T, et al. Chromatography-Free Synthesis of 尾-Carboline 1-Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of 尾-Carbolines as Promising Antifungal and Antibacterial Candidates. J Med Chem. 2023 Jul 13;66(13):9040-9056.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2956809-71-3