Gamma-Glutamyl Transferase-IN-1

Gamma-Glutamyl Transferase-IN-1

• CAS Number: 2956809-71-3
• UNSPSC Description: Gamma-Glutamyl Transferase-IN-1 (compound 4de) is a β-carboline 1-hydrazide inhibitor with antifungal and antibacterial activities, targeting to glutamyltransferase. Gamma-Glutamyl Transferase-IN-1 acts function by resulting the accumulation of reactive oxygen species, destruction of cell membranes, and dysregulation of histone acetylation[1].
• Target Antigen: Fungal
• Type: Reference compound
• Related Pathways: Anti-infection
• Applications: COVID-19-immunoregulation
• Field of Research: Infection
• Assay Protocol: https://www.medchemexpress.com/gamma-glutamyl-transferase-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NNC1=CC=C(F)C=C1)C2=NC(C(N)=O)=CC3=C2NC4=CC=CC=C43
• Molecular Weight: 363.35
• References & Citations: [1]Sheng T, et al. Chromatography-Free Synthesis of 尾-Carboline 1-Hydrazides and an Investigation of the Mechanism of Their Bioactivity: The Discovery of 尾-Carbolines as Promising Antifungal and Antibacterial Candidates. J Med Chem. 2023 Jul 13;66(13):9040-9056.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported