Cisplatin-resistant cells-IN-1

Cisplatin-resistant cells-IN-1

• UNSPSC Description: Cisplatin-resistant cells-IN-1 (Compound 8) has high cytotoxicity against Cisplatin (HY-17394)-resistant cells. Cisplatin-resistant cells-IN-1 reduces the metabolic activity effectively in the low nanomolar range (IC50: 0.14–1.79 μM in A549/A549-R, K562/K562-R, and MCF-7/MCF-7TamR cells)[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cisplatin-resistant-cells-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: CC[n]1c([Au]c2[n](CC)C(C3=CC=CC=C3)=C(C4=CC=CC=C4)[n]2CC)[n](CC)C(C5=CC=CC=C5)=C1C6=CC=CC=C6.F[P-](F)(F)(F)(F)F.[+]
• Molecular Weight: 894.68
• References & Citations: [1]Paul Kapitza, et al. Reaction Behavior of [1,3-Diethyl-4,5-diphenyl-1H-imidazol-2-ylidene] Containing Gold(I/III) Complexes against Ingredients of the Cell Culture Medium and the Meaning on the Potential Use for Cancer Eradication Therapy. J. Med. Chem. 2023, 66, 12, 8238–8250.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported