5’-O-DMTr-3’-O-phthalimidopropyl cytidine

5’-O-DMTr-3’-O-phthalimidopropyl cytidine

• UNSPSC Description: 5’-O-DMTr-3’-O-phthalimidopropyl cytidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/5-o-dmtr-3-o-phthalimidopropyl-cytidine.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@@H]1[C@H](OCCCN2C(C3=CC=CC=C3C2=O)=O)[C@@H](COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)O[C@H]1N7C=CC(N)=NC7=O
• Molecular Weight: 732.78
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported