N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine

• UNSPSC Description:

  N6-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl) adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/n6-benzoyl-3-o-dmt-2-o-2-methoxyethyl-adenosine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC[C@H]1O[C@@H](N(C=N2)C3=C2C(NC(C4=CC=CC=C4)=O)=NC=N3)[C@H](OCCOC)[C@@H]1OC(C5=CC=CC=C5)(C6=CC=C(OC)C=C6)C7=CC=C(OC)C=C7

• Molecular Weight:

  731.79

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported