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2’,5’-Dideoxyuridine

CAT: 0804-HY-154421-01Size: 500 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-154421-01Size:500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
2’,5’-Dideoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
CAS Number
35959-50-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-5-dideoxyuridine.html
Solubility
10 mM in DMSO
Smiles
O=C(C=CN1[C@H]2C[C@H](O)[C@@H](C)O2)NC1=O
Molecular Formula
C9H12N2O4
Molecular Weight
212.20
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

Chemical Information

2',5'-Dideoxyuridine
CAS Number35959-50-3
PubChem CID444320
IUPAC Name1-[(2R,4S,5R)-4-hydroxy-5-methyloxolan-2-yl]pyrimidine-2,4-dione
Molecular FormulaC9H12N2O4
Molecular Weight212.20
XLogP-1.1
Topological Polar Surface Area78.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Heavy Atom Count15
Formal Charge0
Complexity328
SMILES
C[C@@H]1[C@H](C[C@@H](O1)N2C=CC(=O)NC2=O)O
InChI
InChI=1S/C9H12N2O4/c1-5-6(12)4-8(15-5)11-3-2-7(13)10-9(11)14/h2-3,5-6,8,12H,4H2,1H3,(H,10,13,14)/t5-,6+,8-/m1/s1
InChIKey
FDCFKLBIAIKUKB-GKROBHDKSA-N
Chemical Structure
2D Structure
2D structure of 2',5'-Dideoxyuridine
CAS: 35959-50-3
CID: 444320
Formula: C9H12N2O4
MW: 212.20
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight212.20
XLogP3-1.1
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass212.07970687
Monoisotopic Mass212.07970687
Topological Polar Surface Area78.9 Ų
Heavy Atom Count15
Formal Charge0
Complexity328
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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