1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione

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804-HY-154335

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CAS Number: 129885-95-6
UNSPSC Description: 1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/1-3-deoxy-3-fluoro-β-d-xylofuranosyl-2-4-1h-3h-pyrimidinedione.html
Solubility: 10 mM in DMSO
Smiles: OC[C@@H]1[C@H](F)[C@@H](O)[C@H](N2C(NC(C=C2)=O)=O)O1
Molecular Weight: 246.19
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-154335	1-(3-Deoxy-3-fluoro-β-D-xylofuranosyl)-2,4(1H,3H)-pyrimidinedione
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