1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione

• UNSPSC Description:

  1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/1-2-deoxy-2-fluoro-β-d-arabinofuranosyl-5-ethyl-2-4-1h-3h-pyrimidinedione.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@H](F)[C@H](N(C(N2)=O)C=C(CC)C2=O)O[C@@H]1CO

• Molecular Weight:

  274.25

• References & Citations:

  [1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  83546-42-3