1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione

1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione

• CAS Number: 83546-42-3
• UNSPSC Description: 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/1-2-deoxy-2-fluoro-β-d-arabinofuranosyl-5-ethyl-2-4-1h-3h-pyrimidinedione.html
• Solubility: 10 mM in DMSO
• Smiles: O[C@H]1[C@H](F)[C@H](N(C(N2)=O)C=C(CC)C2=O)O[C@@H]1CO
• Molecular Weight: 274.25
• References & Citations: [1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported