3’-beta-Azido-2’,3’-dideoxy-5’-O-(4-methoxy-trityl)uridine

3’-beta-Azido-2’,3’-dideoxy-5’-O-(4-methoxy-trityl)uridine

• CAS Number: 2072145-36-7
• UNSPSC Description: 3’-beta-Azido-2’,3’-dideoxy-5’-O-(4-methoxy-trityl)uridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/3-beta-azido-2-3-dideoxy-5-o-4-methoxy-trityl-uridine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NC(C=C1)=O)N1[C@@H]2O[C@H](COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5)[C@H](N=[N+]=[N-])C2
• Molecular Weight: 525.56
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported