3’-β-Amino-2’,3’-dideoxy-5’-O-methoxy trityluridine

3’-β-Amino-2’,3’-dideoxy-5’-O-methoxy trityluridine

• CAS Number: 2072145-31-2
• UNSPSC Description: 3’-β-Amino-2’,3’-dideoxy-5’-O-methoxy trityluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/3-β-amino-2-3-dideoxy-5-o-methoxy-trityluridine.html
• Solubility: 10 mM in DMSO
• Smiles: N[C@@H]1C[C@H](N(C(N2)=O)C=CC2=O)O[C@@H]1COC(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=C(OC)C=C5
• Molecular Weight: 499.56
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported