4′,5′-Didehydro-5′-deoxyadenosine

CAT:

804-HY-154232

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CAS Number: 20535-04-0
UNSPSC Description: 4′,5′-Didehydro-5′-deoxyadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/4-5-didehydro-5-deoxyadenosine.html
Solubility: 10 mM in DMSO
Smiles: C=C1[C@@H](O)[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2)O1
Molecular Weight: 249.23
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-154232	4′,5′-Didehydro-5′-deoxyadenosine
HY-77645-02	4',5'-Didehydro-5'-deoxyuridine
HY-77645-01	4',5'-Didehydro-5'-deoxyuridine
HY-77645-05	4',5'-Didehydro-5'-deoxyuridine
HY-77645-04	4',5'-Didehydro-5'-deoxyuridine
HY-77645-03	4',5'-Didehydro-5'-deoxyuridine
HY-154345	4′,5′-Didehydro-5′-deoxy-5-methyluridine
HY-154348	4’,5’-Didehydro-5’-deoxy thymidine
HY-154373	4′,5′-Didehydro-2′,5′-dideoxyuridine
HY-113291-05	5'-Deoxyadenosine