4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine

• UNSPSC Description:

  4’,5’-Didehydro-2’,5’-dideoxy-2’-fluorouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/4-5-didehydro-2-5-dideoxy-2-fluorouridine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@@H](F)[C@H](N(C(N2)=O)C=CC2=O)OC1=C

• Molecular Weight:

  228.18

• References & Citations:

  [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1365255-75-9