5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
CAT:
804-HY-W097792-01
Size:
10 mM / 1 mL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine
- CAS Number: 23669-79-6
- UNSPSC Description: 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive inhibitor of E. coli dUTP nucleotidohydrolase (dUTPase), with the Ki higher than 1000 μM. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted DNA synthesis by synthesizing nucleosidic phosphoramidite blocks[1][2].
- Target Antigen: DNA/RNA Synthesis
- Type: Biochemical Assay Reagents
- Related Pathways: Cell Cycle/DNA Damage
- Field of Research: Others
- Assay Protocol: https://www.medchemexpress.com/5-o-4-4-dimethoxytrityl-2-deoxyuridine.html
- Purity: 98.20
- Solubility: DMSO : 100 mg/mL (ultrasonic)
- Smiles: COC1=CC=C(C(C2=CC=C(OC)C=C2)(OC[C@@H]3[C@@H](O)C[C@@H](O3)N4C=CC(NC4=O)=O)C5=CC=CC=C5)C=C1
- Molecular Weight: 530.57
- References & Citations: [1]Hidalgo-Zarco F, et, al. Kinetic properties and inhibition of the dimeric dUTPase-dUDPase from Leishmania major. Protein Sci. 2001 Jul;10(7):1426-33.|[2]Hovinen J, et, al. Versatile strategy for oligonucleotide derivatization. Introduction of lanthanide(III) chelates to oligonucleotides. Org Lett. 2001 Aug 9;3(16):2473-6.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, protect from light)
- Clinical Information: No Development Reported