N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine

• UNSPSC Description:

  N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine (5'-O-DMT-N4-Bz-dC) can be used for synthesis oligodeoxynucleotides containing a 3'-S-phosphorothiolate (3'-PS) linkage. N4-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine is an useful tool for probing enzyme-catalyzed cleavage processes in DNA[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/n4-benzoyl-5-o-4-4-dimethoxytrityl-2-deoxycytidine.html

• Purity:

  99.55

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N=C(NC(C1=CC=CC=C1)=O)C=C2)N2[C@H]3C[C@H](O)[C@@H](COC(C4=CC=C(OC)C=C4)(C5=CC=C(OC)C=C5)C6=CC=CC=C6)O3

• Molecular Weight:

  633.69

• References & Citations:

  [1]James W Gaynor, et al. Synthesis of the 3'-thio-nucleosides and subsequent automated synthesis of oligodeoxynucleotides containing a 3'-S-phosphorothiolate linkage. Nat Protoc. 2007;2(12):3122-35.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  67219-55-0