2’-O-Acetyl-N4-benzoyl-5’-O-DMT arabinocytidine 3’-O-phosphoramidite

2’-O-Acetyl-N4-benzoyl-5’-O-DMT arabinocytidine 3’-O-phosphoramidite

• CAS Number: 675573-97-4
• UNSPSC Description: 2’-O-Acetyl-N4-benzoyl-5’-O-DMT arabinocytidine 3’-O-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-o-acetyl-n4-benzoyl-5-o-dmt-arabinocytidine-3-o-phosphoramidite.html
• Solubility: 10 mM in DMSO
• Smiles: CC(C)N(C(C)C)P(O[C@H]1[C@H](OC(C)=O)[C@H](N2C=CC(NC(C3=CC=CC=C3)=O)=NC2=O)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6)OCCC#N
• Molecular Weight: 891.94
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported