2’-Deoxy-2’-fluoroadenosine 5’-monophosphate (triethylammonium)

2’-Deoxy-2’-fluoroadenosine 5’-monophosphate (triethylammonium)

• UNSPSC Description: 2’-Deoxy-2’-fluoroadenosine 5’-monophosphate (triethylammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-deoxy-2-fluoroadenosine-5-monophosphate-triethylammonium.html
• Solubility: 10 mM in DMSO
• Smiles: CCN(CC)CC.CCN(CC)CC.O[C@H]1[C@@H](F)[C@H](N2C(N=CN=C3N)=C3N=C2)O[C@@H]1COP(O)(O)=O
• Molecular Weight: 551.59
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported