JGK-068S

• Description:

  JGK-068S (compound I) is a potent EGFR inhibitor[1].

• UNSPSC:

  12352005

• Target:

  EGFR

• Type:

  Reference compound

• Related Pathways:

  JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/jgk-068s.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN(CC1)CCN1C[C@@H]2OC3=CC(C(NC4=C(C(Br)=CC=C4)F)=NC=N5)=C5C=C3OC2

• Molecular Formula:

  C22H23BrFN5O2

• Molecular Weight:

  488.35

• References & Citations:

  [1]Fritz Blatter, et al. Egfr inhibitor polymorph forms. WO2023049312A1.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  EGFR/ErbB1/HER1

• CAS Number:

  [2490431-16-6]