JAK-IN-28

CAT: 0804-HY-153712Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-153712Size:1 Each

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Description

JAK-IN-28 (Compound 111) is a JAK inhibitor. JAK-IN-28 can be used for research of cancer or inflammatory diseases[1].

CAS Number

2445500-22-9

UNSPSC

12352005

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/jak-in-28.html

Solubility

10 mM in DMSO

Smiles

ClC1=CN=C(NC2=CN(C3CC3)N=C2)N=C1C4=CC=C(C=C4)C(N[C@@H](C)C#N)=O

Molecular Formula

C20H18ClN7O

Molecular Weight

407.86

References & Citations

[1]Wan Zhaokui, et al. Benzamides of pyrazolyl-amino-pyrimidinyl derivatives, and compositions and methods thereof. Patent. WO2020119819. 2020-06-18.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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