BacPROTAC-1

CAT: 0804-HY-153575-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-153575-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

BacPROTAC-1 is a mSA BacPROTAC degrader. BacPROTAC-1 binds mSA and ClpCNTD with high affinity (KDs of 3.9 and 2.8 μM, respectively) [1].

UNSPSC

12352005

Target

Bacterial; PROTACs

Type

Reference compound

Related Pathways

Anti-infection; PROTAC

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bacprotac-1.html

Solubility

10 mM in DMSO

Smiles

O=C(NCCCC[C@H](NC(CCOCCOCCNC(CCOCCOCCNC(CCOCCOCCNC([C@H](CCCNC(NP(O)(O)=O)=N)NC(C)=O)=O)=O)=O)=O)C(N)=O)CCCC[C@@H]1SC[C@@H]([C@@H]1N2)NC2=O

Molecular Formula

C45H83N12O17PS

Molecular Weight

1127.25

References & Citations

[1]Morreale FE, et al. BacPROTACs mediate targeted protein degradation in bacteria. Cell. 2022 Jun 23;185 (13) :2338-2353.e18.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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