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Homo-BacPROTAC7

CAT: 0804-HY-153572Size: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-153572Size:Inquire
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UNSPSC Description
Homo-BacPROTAC7 is a ClpC1NTD BacPROTAC degrader and can targets ClpC2. Homo-BacPROTAC7 efficiently kill M. tuberculosis[1].
Target Antigen
Bacterial; PROTACs
Type
Reference compound
Related Pathways
Anti-infection;PROTAC
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/homo-bacprotac7.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@H](C(N(C)[C@H](C(N[C@@H](CC1=CN(CCCCCN2N=NC(C[C@H](NC([C@@H](N(C)C([C@H](C(C)C)NC([C@H]([C@@H](C3=CC=CC=C3)OC)NC([C@H](C)NC([C@@H](N4C)C[C@@H](C)CO)=O)=O)=O)=O)CC(C)C)=O)C(N[C@@H](CC5=CN(C)C6=C5C=CC=C6)C4=O)=O)=C2)N=N1)C(N[C@@H](CC7=CN(C)C8=C7C=CC=C8)C9=O)=O)=O)CC(C)C)=O)C(C)C)[C@@H](NC([C@H](C)NC([C@H](C[C@H](CO)C)N9C)=O)=O)[C@H](OC)C%10=CC=CC=C%10
Molecular Weight
1980.40
References & Citations
[1]Hoi DM, et al. Clp-targeting BacPROTACs impair mycobacterial proteostasis and survival. Cell. 2023 May 11;186(10):2176-2192.e22.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported

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