AP-C7

• Description :

  AP-C7 is an inhibitor of guanosine 3′,5′-cyclic monophosphate (cGMP) -dependent protein kinase II (cGKII) with a pIC50 of 5.0. AP-C7 only weakly inhibits cGKII-dependent anion secretion[1].

• UNSPSC :

  12352005

• Target :

  PKG

• Type :

  Reference compound

• Related Pathways :

  Stem Cell/Wnt

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/ap-c7.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N1(C2=CC=C(C3=NC(NCC4=CC=CO4)=NC=C3)C=C2)C=CN=C1

• Molecular Formula :

  C18H15N5O

• Molecular Weight :

  317.34

• References & Citations :

  [1]Marcel J C Bijvelds, et al. Selective inhibition of intestinal guanosine 3',5'-cyclic monophosphate signaling by small-molecule protein kinase inhibitors. J Biol Chem. 2018 May 25;293 (21) :8173-8181.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2234275-84-2]