Products for Research Use Only
RegisterLogin

Cimdelirsen (sodium)

CAT: 0804-HY-153485ASize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-153485ASize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Cimdelirsen is a novel, ligand-conjugated, hepatic-targeted investigative antisense oligonucleotide designed to reduce growth hormone receptor (GHr) synthesis, thereby inhibiting deleterious effects of growth hormone (GH) hypersecretion and reducing circulating insulin-like growth factor-1 (IGF-1) levels in acromegaly patients.
CAS Number
2131025-83-5
Product Name Alternative
ISIS 766720 (sodium) ; IONIS-GHR-LRx (sodium)
UNSPSC
12352208
Target
GHR; Small Interfering RNA (siRNA)
Type
Oligonucleotides
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/cimdelirsen-sodium.html
Solubility
10 mM in H2O
Smiles
[Cimdelirsen(sodium)]
Molecular Formula
C296H415N83Na20O152P20S15
Molecular Weight
8688.55 (free acid)
References & Citations
[1]Bhanot S, Fleseriu M, Geary R, et al. OR27-4 Placebo-Controlled and Open-Label Extension Study of a Novel Hepatic-Targeted Antisense Cimdelirsen (IONIS-GHR-LRx) Under Investigation in Acromegaly Patients. J Endocr Soc. 2022;6 (Suppl 1) :A526.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
Phase 2

Related Products

CatalogName
HY-153485Cimdelirsen
HY-N15194AInostamycin A (sodium)
HY-166084Docosatetraenoate (sodium)
HY-16366ABriciclib (sodium)
HY-150364AFarabursen (sodium)
HY-107943Tyropanoate (sodium)
HY-W009640AMofebutazone (sodium)
HY-22274-01DMPG (sodium)
HY-17474A-01Parecoxib (Sodium)
HY-148089A-01Eplontersen (sodium)

Alternative Products

CatalogName
1191110 500Sodium Metabisulphite (Sodium Disulphite, Sodium Pyrosulphite)
RM-T081600-01Thiopental Sodium And Sodium Carbonate
21121001-100gSodium caprylate- (Sodium octanoate)
GTR19178128-01Emlenoflast sodium (MCC7840 sodium)
AR-M08542-01Nadroparin Sodium (Heparin Sodium)
31112-64Sodium
030180-01Sodium Metabisulphite (Sodium Disulphite, Sodium Pyrosulphite) 95.0%
85254-01Cefoperazone Sodium (CFZ, Cefaperazone Sodium)
77969456Sodium thiomethoxide (Sodium methyl mercaptide)
10878741-01Sodium bisulfite (Sodium hydrogen sulfite)

Popular Products