N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine

N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine

• CAS Number: 2243974-78-7
• UNSPSC Description: N2-iso-Butyroyl-7'-O-DMT-morpholinoguanine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/n2-iso-butyroyl-7-o-dmt-morpholinoguanine.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N=C(N1)NC(C(C)C)=O)C(N=C2)=C1N2[C@@H](CNC3)O[C@@H]3COC(C4=CC=C(C=C4)OC)(C5=CC=CC=C5)C6=CC=C(C=C6)OC
• Molecular Weight: 638.71
• References & Citations: [1]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported