N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine

N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine

• CAS Number: 2080404-19-7
• UNSPSC Description: N2-iso-Butyroyl-5'-O-DMT-3'-deoxy-3'-fluoroguanosine is a guanosine analog. Some guanosine analogs have immunostimulatory activity. In some animal models, they also induce type I interferons, producing antiviral effects. Studies have shown that the functional activity of guanosine analogs is dependent on the activation of Toll-like receptor 7 (TLR7)[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Oligonucleotides
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n2-iso-butyroyl-5-o-dmt-3-deoxy-3-fluoroguanosine.html
• Solubility: 10 mM in DMSO
• Smiles: F[C@H]1[C@@H](O)[C@H](N2C(N=C(NC(C(C)C)=O)NC3=O)=C3N=C2)O[C@@H]1COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6
• Molecular Weight: 657.69
• References & Citations: [1]Lee J, et al. Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: activation of Toll-like receptor 7. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6646-51.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported