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JTV-519

CAT: 0804-HY-15293Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-15293Size:1 Each
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Description
JTV-519 (K201) is a Ca2+-dependent blocker of sarcoplasmic reticulum Ca2+-stimulated ATPase (SERCA) and a partial agonist of ryanodine receptors in striated muscle. Antiarrhythmic and cardioprotective properties[1][2].
CAS Number
1038410-88-6
Product Name Alternative
K201
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/jtv-519.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C2C(CN(C(CCN3CCC(CC4=CC=CC=C4)CC3)=O)CCS2)=C1.Cl
Molecular Formula
C25H33ClN2O2S
Molecular Weight
461.06
References & Citations
2+2+
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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