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8-Methoxyadenosine

CAT: 0804-HY-152834Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152834Size:1 Each
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Description
8-Methoxyadenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine , Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277).
CAS Number
3969-27-5
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-methoxyadenosine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(C(OC)=N2)C3=C2C(N)=NC=N3)O1
Molecular Formula
C11H15N5O5
Molecular Weight
297.27
References & Citations
[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.|[2]Cheeseman MD, Westwood IM, Barbeau O, et al. Exploiting Protein Conformational Change to Optimize Adenosine-Derived Inhibitors of HSP70. J Med Chem. 2016;59 (10) :4625-4636.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported