2'-Deoxy-2'-fluoro-5-trifluoromethyl-arabinouridine

• UNSPSC Description:

  2′-Deoxy-2′-fluoro-5-triflu oromethyl-arabinouridine is a thymidine analogue. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].

• Target Antigen:

  Nucleoside Antimetabolite/Analog

• Type:

  Oligonucleotides

• Related Pathways:

  Cell Cycle/DNA Damage

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/2-deoxy-2-fluoro-5-trifluoromethyl-arabinouridine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O[C@H]1[C@H](F)[C@H](N(C(N2)=O)C=C(C(F)(F)F)C2=O)O[C@@H]1CO

• Molecular Weight:

  314.19

• References & Citations:

  [1]Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  114652-80-1