9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin

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804-HY-W334680

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CAS Number: 103884-98-6
UNSPSC Description: 2-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-6H-purin-6-one (9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Reference compound
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Others
Assay Protocol: https://www.medchemexpress.com/9-β-d-2-fluoro-2-deoxy-arabinofuranosyl-guanin.html
Solubility: 10 mM in DMSO
Smiles: O[C@H]1[C@H](F)[C@H](N2C=NC3=C2NC(N)=NC3=O)O[C@@H]1CO
Molecular Weight: 285.23
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-W334680	9-β-D-[2'-Fluoro-2'-deoxy-arabinofuranosyl]-guanin
HY-152780	9-(2’-Deoxy-2’-fluoro-β-D-arabinofuranosyl)-9H-purine
HY-152776	2-Amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine
HY-152773	2,6-Diamino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-9H-purine
HY-152686	2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine
HY-W700460	9-β-D-Arabinofuranosyl-2-fluorohypoxanthine
HY-W017749-01	1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
HY-W017749-03	1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
HY-W017749-02	1-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)uracil
HY-152676	1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-ethyl-2,4(1H,3H)-pyrimidinedione

Cat	Name
TRC-D239970-100MG	9-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)guanine
sc-207212	9-β-D-Arabinofuranosyl-2-fluorohypoxanthine
BIMN2021-02	9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine (FANA-A)
BIMN2023-01	9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine (2’-FANA-G)
BIMN2024-01	9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)hypoxantine (2’-FANA-I)
BIMN2021-01	9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine (FANA-A)
BIMN2023-02	9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)guanine (2’-FANA-G)
BIMN2024-02	9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)hypoxantine (2’-FANA-I)
sc-281782A	1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil
sc-281782	1-(2'-Deoxy-2'-fluoro-b-D-arabinofuranosyl)uracil