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3’-β-C-Ethynyluridine

CAT: 0804-HY-152476Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152476Size:1 Each
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Description
3’-β-C-Ethynyluridine is a uridine analog. Uridine has potential antiepileptic effects, and its analogs can be used to study anticonvulsant and anxiolytic activities, as well as to develop new antihypertensive agents[1]. 3’-β-C-Ethynyluridine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
CAS Number
180300-49-6
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-β-c-ethynyluridine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@](O)(C#C)[C@@H](O)[C@H](N(C=C2)C(NC2=O)=O)O1
Molecular Formula
C11H12N2O6
Molecular Weight
268.22
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.|[2]Connolly GP, et al. Uridine and its nucleotides: biological actions, therapeutic potentials. Trends Pharmacol Sci. 1999 May;20 (5) :218-25.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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