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N1-Methyl-arabinoadenosine

CAT: 0804-HY-152464Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-152464Size:1 Each
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Description
N1-Methyl-arabinoadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
CAS Number
685880-77-7
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/n1-methyl-arabinoadenosine.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@H](O)[C@H](N(C=N2)C3=C2C(N(C)C=N3)=N)O[C@@H]1CO
Molecular Formula
C11H15N5O4
Molecular Weight
281.27
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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