N1-Methyl-2'-deoxyadenosine

N1-Methyl-2'-deoxyadenosine

• CAS Number: 60192-55-4
• UNSPSC Description: N1-Methyl-2'-deoxyadenosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/n1-methyl-2-deoxyadenosine.html
• Solubility: DMSO : 125 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)
• Smiles: OC[C@@H]1[C@@H](O)C[C@H](N2C(N=CN(C)C3=N)=C3N=C2)O1
• Molecular Weight: 265.27
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room Temperature
• Clinical Information: No Development Reported