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6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one

CAT:
804-HY-152405
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one - image 1

6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one

  • UNSPSC Description:

    6-Amino-1,2-dihydro-2-β-D-ribofuranosyl-4H-pyrazolo[3,4-d]pyrimidin-4-one is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • Target Antigen:

    Nucleoside Antimetabolite/Analog

  • Type:

    Oligonucleotides

  • Related Pathways:

    Cell Cycle/DNA Damage

  • Applications:

    Cancer-programmed cell death

  • Field of Research:

    Others

  • Assay Protocol:

    https://www.medchemexpress.com/6-amino-1-2-dihydro-2-β-d-ribofuranosyl-4h-pyrazolo-3-4-d-pyrimidin-4-one.html

  • Solubility:

    10 mM in DMSO

  • Smiles:

    O[C@H]1[C@@H](O)[C@H](N2NC=C3C2=NC(N)=NC3=O)O[C@@H]1CO

  • Molecular Weight:

    283.24

  • References & Citations:

    [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

  • Shipping Conditions:

    Room temperature

  • Clinical Information:

    No Development Reported

  • CAS Number:

    85426-86-4

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