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6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

CAT:
804-HY-152414
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  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine - image 1

6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

  • UNSPSC Description:

    6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

  • Target Antigen:

    Nucleoside Antimetabolite/Analog

  • Type:

    Oligonucleotides

  • Related Pathways:

    Cell Cycle/DNA Damage

  • Applications:

    Cancer-programmed cell death

  • Field of Research:

    Others

  • Assay Protocol:

    https://www.medchemexpress.com/6-amino-4-hydroxyamino-2-β-d-ribofuranosyl-2h-pyrazolo-3-4-d-pyrimidine.html

  • Solubility:

    10 mM in DMSO

  • Smiles:

    O[C@H]1[C@@H](O)[C@H](N2N=CC3=C2N=C(N)N=C3NO)O[C@@H]1CO

  • Molecular Weight:

    298.26

  • References & Citations:

    [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

  • Shipping Conditions:

    Room temperature

  • Clinical Information:

    No Development Reported

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