4-Methoxy-1-β-D-ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine

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804-HY-152827

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CAS Number: 1611486-54-4
UNSPSC Description: 4-Methoxy-1-β-D-ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Target Antigen: Nucleoside Antimetabolite/Analog
Type: Oligonucleotides
Related Pathways: Cell Cycle/DNA Damage
Applications: Cancer-programmed cell death
Field of Research: Cancer
Assay Protocol: https://www.medchemexpress.com/4-methoxy-1-β-d-ribofuranosyl-1h-pyrazolo-3-4-d-pyrimidin-6-amine.html
Solubility: 10 mM in DMSO
Smiles: OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(N=C2)C3=C2C(OC)=NC(N)=N3)O1
Molecular Weight: 297.27
References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-152827	4-Methoxy-1-β-D-ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine
HY-154008	6-Amino-4-methoxy-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
HY-152438	6-Amino-3-ethynyl-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
HY-152398	6-Amino-4-methoxy-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine
HY-152443	6-Amino-3-(furan-2-yl)-4-methoxy-1-(β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
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HY-154122	6-Amino-4-methoxy-1-(2-deoxy-a-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
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HY-154047	6-Amino-4-hydrozino-1-(2-deoxy-β-D-ribofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine
HY-152414	6-Amino-4-hydroxyamino-2-(β-D-ribofuranosyl)-2H-pyrazolo[3,4-d]pyrimidine

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