Tankyrase-IN-3

• UNSPSC Description:

  Tankyrase-IN-3 is a tankyrase 1 (TNKS1) inhibitor with an IC50 value of 22 nM. Tankyrase-IN-3 can be used for the research of cancer[1].

• Target Antigen:

  PARP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tankyrase-in-3.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OCC(N1CCN(CC1)C2=CC=CC=N2)=O)CC(C3=CC=CC=C34)=NNC4=O

• Molecular Weight:

  407.42

• References & Citations:

  [1]Alba L Montoya, et al. Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors. Eur J Med Chem. 2023 Jan 15;246:114980.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  938893-79-9