Tankyrase-IN-4

• UNSPSC Description:

  Tankyrase-IN-4 is a tankyrase 1 (TNKS1) inhibitor with an IC50 value of 0.8 nM. Tankyrase-IN-4 can be used for the research of cancer[1].

• Target Antigen:

  PARP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/tankyrase-in-4.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CNC([C@@H](NC(C1=CN=C2C=CC=CC2=C1)=O)CNC(CCN3C(NC(C4=C3C=CC=C4)=O)=O)=O)=O

• Molecular Weight:

  488.50

• References & Citations:

  [1]Alba L Montoya, et al. Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors. Eur J Med Chem. 2023 Jan 15;246:114980.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported